Simple steps to minimize Column bleed from GC columns

Reduction of column bleed requires first of all a clear understanding of the term. Column bleeding results from thermal breakdown of the stationary phase at temperatures close to the upper temperature limit of the column. The level of bleed depends on the film thickness of the stationary phase layer on the adsorbent. Thick films columns […]

Sampling of Gases for analysis by Gas Chromatography

Gas chromatography is an ideal tool for analysis of gases. The versatility of the technique extends its capability to analyse samples such as dissolved solids, liquids and gases. The scope of applications extends from pharmaceuticals, foods, environmental monitoring, petroleum refining, and workplace environment monitoring for safety of workers. Gas samples require special handling as gases […]

Benefits offered by automated injection in Gas Chromatography

Manual syringe injection is the most popular gas chromatography sample injection practice adopted in laboratories across the world. The obvious reason for this choice is convenience and low price of syringes. However, keep in mind that it may take considerable time to perfect the skills required to inject volumes with high accuracy and precision. Bear […]

How to minimize retention time drifts in Gas Chromatography?

Retention time drifts contribute to wastage of time and undue frustration during analytical chromatographic runs. It is defined as the time that the particular compound spends in the column between its injection and detection. In other words it is the time that elapses between its injection and the maximum of its peak response. It helps […]

Familiarize with the Gas Chromatograph

A Gas Chromatograph like any other analytical instrument has evolved from one with several knobs and dials to one having a simple microprocessor based keypad to control the operational parameters. The simplification has resulted in ease of operation and time saving. An understanding of the main component parts will help in maximum utilization of system capabilities.

Tips on improving accuracy and precision of Gas Chromatographic injections

The accuracy and precision of Gas Chromatographic analysis depends to a significant extent on your skill to use the injection syringe. It is possible to achieve a precision of manual injection volumes less than 1% RSD once you have gained mastery on sample injections. Proper handling and care of chromatographic syringes has been dealt with earlier. […]

Troubleshooting Tips for Gas Chromatographic Syringe

Gas chromatographic syringe is an indispensable accessory for the gas chromatographer. Syringe is necessary for introduction of selected volume into the gas chromatograph. The results of analysis are meaningful only if the selected volumes are accurately and reproducibly transferred into the system. Proper handling and care of chromatographic syringes has been covered earlier. However, in addition […]

Certificate Course on Gas Chromatography now available!

Finally the wait is over. Since the launch of our certificate courses on HPLC and Atomic Absorption Spectroscopy we have received several requests for a similar Course on Gas Chromatography. It has taken considerable time to develop the course as GC has wide-ranging applications in diverse areas and consolidation of details proved to be time-consuming. […]

Recommendations for switching from Gas cylinders to Laboratory gas generators

Industrial laboratories in sectors such as petroleum and petrochemicals, foods, flavours and fragrances and pharmaceuticals can house scores of gas chromatographs or their modified versions for specific applications. Such systems are bulk consumers of high purity gases such as nitrogen, helium, hydrogen and zero air 24 hours a day throughout the year. Even big R&D […]

What is Multi- dimensional GC?

Under normal GC operation a single column is mounted inside the column oven. This works fine with most common laboratory separations involving limited number of sample constituents (say,5 – 10). However, as the number of components having similar boiling points increases a single column is generally not sufficient to give the required resolution between the […]

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