How to Choose a Gas Chromatographic Detector for my Analysis?

In Gas Chromatography detection is based on a property of the eluting compound which is different from the carrier gas. It is necessary to have a clear understanding of your analysis requirements in advance before you can decide on the suitability of the detector. Important considerations are: Is the detector Destructive or Nondestructive. Nondestructive detectors […]

Why is Leak checking necessary before starting Gas Chromatography analysis?

A Gas Chromatographic system which is ready for analysis should be free of line leakages to give precise results every time  under identical conditions. Gas leaks   can be frustrating due to the following reasons: Leaks lead to loss of expensive high-quality gases Flow changes due to leaks result in shifting of peak positions due to […]

GC Free E-Course : Introduction to Gas Chromatography

Gas Chromatography is widely used for separation, identification and quantification of mixtures of liquids and gases. The majority of Gas Chromatography applications are found in Petroleum and Petro chemicals, Pharmaceuticals, Food & Flavors, Environmental and Forensics. The scope has widened through evolution of hyphenated techniques such as GC-MS, GC-FT-IR, GC-HS, etc which are capable of […]

Benefits of Split /Splitless Injection in Capillary Gas Chromatography

Benefits of split/splitless injection in Gas Chromatographic detection gives you the freedom of changing the amount of sample component entering the capillary column. Splitless mode – Split Valve Closed Split mode – Split Valve Partialy open At times you may get a broad flat top peak instead of a sharp well-defined peak. In such situations […]

Four Key Considerations for choice of Capillary Gas Chromatographic Columns

The choice of a Capillary Gas Chromatography column is based on four important considerations: Stationary phase Column length Column ID Film thickness First Consideration – Stationary Phase Separation sequence of eluting compounds depends upon physico – chemical interactions between the compounds and the stationary phase. Each phase has specific interactions with different groups of analytes […]