Hyphenated Chromatographic Techniques: GC – MS and LC – MS

Chromatographic techniques have proved to be invaluable for their contribution in areas of chemical research and quality control. The application areas and sensitivity of detection have improved significantly with the introduction of hyphenated techniques such as GC-MS and LC – MS.

LC – MS combines the physical separation ability of liquid chromatography with the mass discrimination potential of mass spectroscopy to achieve unforeseen levels of identification and quantification. Major development of MS-MS allows programmed separation and fragmentation of selected ion masses. Important application areas are bioanalytical studies, new drug development and bio molecule separations, etc.

GC – MS, like LC – MS, is a highly sensitive technique for detection and quantification of volatile organic compounds. The technique is finding applications in the petroleum and petrochemical industry, pharmaceuticals, fragrances and flavours, pesticide residue analysis and environmental monitoring.

The programme will be beneficial for: