Scope of ICP-MS applications

ICP-MS is acclaimed widely as the most sensitive and accurate technique for analysis of traces metals. It has an established application base in studies on pharmaceutical and food products. However, there are some other areas as well where ICP-MS has made inroads and regulatory bodies across the world have specified ICP-MS as the recommended technique […]

Differences between flame and plasma excitation sources in trace metal analysis systems

An excitation source is an essential requirement for trace metal determinations. The two well established techniques are Flame Atomic Absorption Spectroscopy (AAS) and Inductively Coupled Plasma Spectroscopy (ICP) both of which require an excitation source.AAS commonly makes use of a flame whereas ICP employs a plasma excitation source. A question now arises that are both flame […]

Innovative options that expand capabilities of your ICP – MS

ICP – MS provides trace element concentrations in ppb and sub- ppb level concentrations. The analysis normally requires dissolution of solid sample in solution prior to analysis. The article reviews three innovative options that expand the applications many fold and contribute significantly to the laboratory throughput. Collision cells for removal of polyatomic species ICP – […]

Daily Visual checks to prolong useful life of your ICP-MS system

ICP-MS is a well established technique capable of giving highly reliable results day after day for years together. It only requires good care and sound training in sample preparation and handling practices which you can acquire easily over a period of time. ICP-MS involves heavy initial investment and running costs but the costs can be […]

ICP-MS Interferences and their Removal

ICP-MS is a versatile and established technique for trace metal analysis for elements ranging from Li (Atomic mass 7) to Uranium (Atomic mass 250) in ppb, sub- ppb and even ppt levels. However, like any other trace metal analysis ICP-MS is also not free from interferences. Types of Interferences Isobaric Interferences Isobaric interferences result due […]

How to prevent accidents in ICP-MS laboratory?

The design of modern ICP-MS systems incorporates several inbuilt safety features which prevent accidents. However, it is a well established fact that accidents are caused mostly due to carelessness and overconfidence and can be easily prevented if safety instructions are not overlooked. It goes without saying that the instrument should be installed in a clean […]

Which is a better choice?- ICP-OES or ICP-MS

ICP-OES and ICP-MS are preferred techniques for trace and ultra-trace metal estimations. Merits and demerits of both techniques alongwith Graphite furnace Atomic Absorption Spectroscopy have been discussed earlier.The present article will help you decide between the two based on your budget and analysis requirements. Initial Cost The initial cost is a limiting factor for most […]

Potential Sources of Contamination and their control in Ultra- Trace level determination rooms

Ultra trace metal studies have evoked immense importance in the recent past due to increased awareness of potential risks of metallic impurities even at very low concentrations. This has opened up new avenues and applications of sophisticated techniques such as Graphite furnace AAS,ICP-OES, ICP-MS, Nuclear activation analysis , X-Ray Fluorescence and Isotopic Dilution Mass Spectroscopy. […]

What are important considerations for trace metal analysis?

Trace metal analysis is referred to as analysis of elements in different matrices at levels below one ppm. The article Which technique should I use for trace metal analysis is a refresher on the common techniques used for trace metal analysis. Trace metal analysis has posed a perpetual challenge to skills of the analytical chemist […]

ICP – MS: A versatile tool for Trace Element studies

Trace elements play a crucial role in deciding the properties and behaviour of materials of everyday use such as foods and beverages, pharmaceuticals, clinical and forensic specimens and environmental samples. Trace elements analysis becomes essential for evaluation of soils for different crops and understanding the nutritional benefits of edible products. A brief introduction to the commonly used […]

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